In 1976, he starred in his final movie, a Western called The Shootist which also featured Lauren Bacall, Ron Howard and James Stewart.

His lead role as JB Books was a man dying from cancer, a disease which would kill Duke in real life just three years later. Having been diagnosed with stomach cancer, Wayne enrolled in a vaccine study in an attempt to beat it. However, the 72-year-old was too weak to begin chemotherapy and experimental treatment.

His last public appearance would be at the 51st Academy Awards on April 9, 1979, where Duke presented Best Picture. He was welcomed to the stage after being introduced by Johnny Carson, arriving to a standing ovation. Wayne was noticeably much thinner and secretly wore a wet suit under his tuxedo to beef himself up. Thanking the audience for their applause, the Western legend spoke before announcing The Deer Hunter as the winner.

He said: “Thank you, ladies and gentlemen. That’s just about the only medicine a fella would really ever need. Believe me when I tell ya, I’m mighty pleased that I can amble down here tonight. Well, Oscar and I have something in common: Oscar first came to the Hollywood scene in 1928, so did I. We’re both a little weather-beaten, but we’re still here and plan to be around for a whole lot longer.”

Sadly Wayne died just two months later on June 11, 1979 with his family around him. His daughter Aissa held his hand and asked if he knew who she was and he replied with his last words.

Duke said sweetly: “Of course, I know who you are. You’re my girl. I love you.” Shortly before he died, the 72-year-old converted to Roman Catholicism and asked that his tombstone read, “Feo, Fuerte y Formal”, a Spanish epitaph meaning “ugly, strong and dignified.”